Aspirin Low Dose used to Reduce the Risk for Stroke for Women Under the Age of 60

Aspirin low dose used to reduce the risk for stroke for women under the age of 60
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Aspirin low dose used to reduce the risk for stroke for women under the age of 60
Introduction
Stoke has become a major catastrophe in the society. It causes disability, impaired functionality, and reduced quality of life. Experts have reviewed evidence and recommendation for a low dosage of aspirin to women under the age of 60 since it is effective in reducing the risk of stroke. Aspirin is highly recommended since it is affordable, there is no need for extensive monitoring, and it is effective in stroke prevention. A low dosage of aspirin is effective for both primary and secondary prevention. However, in primary prevention net, absolute reductions in stroke are minimal while it is high in secondary prevention. There is a great assurance of reduction of stroke with a low dosage of aspirin.
Appreciation of Aspirin Benefits
Recognition of aspirin benefits requires the knowledge of the mechanism of action and the pathophysiology of atherosclerosis. These mechanisms help the body to develop features that fight the consistency of stroke-causing agents in the body. Atherosclerosis is a chronic inflammatory reaction caused by aspirin, which hardens arterial vessels (Ansara,Nisly, Arif,Koehler and Nordmeyer, 2010). The process leads to activation of platelets, which helps in vascular injury repair. Aspirin inhibits vascular difficulties by preventing the effects of platelets. It also prevents thrombosis by hindering the release of the prostanoid TXA2, done by affecting the cyclooxygenase enzymes directly. Additionally, aspirin low dosage aids in dose-dependent platelet inhibition, elevation of fibrinolysis, and dominance of plasma coagulation factors.
Selecting an Optimal Dosage
When choosing an aspirin dosage, it is important to consider bleeding risk, contraindications, and concurrent treatment. Health practitioners must pay attention to dosages that have been proven efficacious for women under the age of 60. High doses of aspirin are only warranted for treatment of ischemic stroke and frequently for stroke prevention in the situation of AF (Dehmer, Maciosek and Flottemesch, 2013). However, high doses contribute to bleeding risks, and as a result, doctors prescribes low doses of less than 100mg daily in prevention and treatment of stroke. At first, doctors highly opposed prescription of a low dosage of aspirin to women under the age of 60 since the risk of aspirin-related gastrointestinal bleeding was rampant but after several studies, the benefits outweighed the negative outcomes.
Primary Prevention of Stroke
The aspirin efficacy for primary prevention of stroke for women under the age of 60 is 100mg daily. Primary prevention in the case of stroke means an adverse medical result before the onset of the disease. Preventing the first incidence of stroke is essential since it prepares the body to be repulsive to any extent that may trigger stroke (Patrono, 2013). The Women’s Health Study is responsible for the study of the effectiveness of aspirin in women. Their study involved subjecting some women to research where they were prescribed with aspirin. They acquired positive result where the num...