The key role of the immune system in psiorisis. Research Paper

Key Role of the Immune System in treating Psoriasis
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August 8, 2018
The Immune System
Being an autoimmune condition, the body’s immune system plays a fundamental part in the development of psoriasis. Usually, the body’s immune system only responds to threats such as viruses and bacteria. Under normal conditions, foreign bodies (including dead cells and tissues) are recognized by accessory cells while white blood cells do the work of ingesting and destroying them. Mainly, there are two main types of WBC’s in the body, the phagocytes, and the lymphocytes. While there are different types of phagocytes, almost all of them function as the initial defense for unrecognized foreign bodies in the bloodstream and the interstitial fluids (Murrell, 2018). In contrasts, lymphocytes (B and T lymphocytes) serve the body, by keeping track of any foreign bodies that have already infected (or existed within) the body in order to provide a quick response against them.
Autoimmune Diseases
As stated earlier, the body’s immune system usually functions according to the processes and conditions discussed previously. However, some conditions that are caused by either external or internal factors could cause abnormalities in the Immune system. Specifically speaking, some of these abnormalities could confuse the immune system and overreact (thereby attacking the body’s cells and tissues) or fail to react when it is most needed (Medlineplus.gov, n.d.). One example of the immune system’s overreaction that causes intense inflammation in the skin and painful joints (among other complications) is Psoriasis.
Psoriasis
Being an autoimmune response, Psoriasis is caused by the immune system’s failure to control its mechanisms thereby causing an acceleration of its processes. When this happens either a swollen, chaffed-like appearance could appear in the skin (psoriasis) or be felt in joints (psoriatic arthritis) (National Psoriasis Foundation, n.d.). Precisely, the overreaction of the body’s immune system could happen in two interactions between the T-cell and the antigen-presenting cell (APC). An APC is a type of white blood cell that identifies and binds with foreign bodies. During an immune response, these APC’s major histocompatibility complexes (MHCs) bind itself with the T-cell Receptors (TCRs) in a sub-process known as antigen presentation (Alberts, Johnson, & Lewis, 2002). Consequently, the first interaction starts with the T-cells circulating throughout the whole system while looking for antigens. During this phase, an APC that has already detected a foreign b...