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Sliding Filament Model of Muscle Fiber Contraction and the Roles of ATP and Calcium
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Muscle Fiber Contraction
View the animation of actin and myosin interaction at http://www(dot)sci(dot)sdsu(dot)edu/movies/actin_myosin_gif.html
Explain the "sliding filament" model of muscle fiber contraction. What are the roles of ATP and calcium?
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Muscle Fiber Contraction
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The Sliding Filament Model
The sliding filament model explains the mechanism of muscle contraction. The striate muscles, i.e., actin and myosin, are involved, where actin slides over myosin, causing the shortening of myofibrils (Powers et al., 2021). ATP plays a crucial role in releasing myosin from actin filaments. It is during muscle contraction that myosin is attached to actin filaments. According to Powers et al. (2021), ATP releases myosin by attaching it to its head and causing it to be released from actin. The resulting effect is muscle relaxation.
The actin and myosin interaction causes cells to move across surfaces. The actin filaments possess binding sites for myosin. The sites are realized when binding between calcium ions and troponin molecules occur (Powers et al., 2021). The process effectively facilitates a bridge formation between ac...
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