What is the association between multiple sclerosis and identifying factors in pediatric patients?

This assignment addresses the following module outcomes:
MO2: Evaluate the ideas and arguments in a variety of sources. (CO2, CO3)
MO4: Synthesize ideas and information from a variety of sources to form a coherent argument essay. (CO1, CO2, CO3)
M3A1: The Argument Essay will be assessed with the following rubric for this assignment:
Argument Essay Rubric [PDF File size, 168KB]
This essay, which identifies a research question or problem, presents a range of interdisciplinary critical scholarly information and then draws conclusions which are supported by the research. The essay should be 8-10 double-spaced pages, not counting the References (APA style) or Works Cited (MLA style), title page, or abstract. It should include at least eight high quality, relevant sources.
In this paper, you should:
Include a thesis statement in your introduction (which may be 1-2 paragraphs long);
Hand in an outline of your paper by the end of Week 1 (M3A1);
Continue research on the topic you have been working on by finding more research that will help you present and respond to the opposition, as well as more research that will help support your position;
Make sure you deal with the opposition to your claim (or any of your reasons) in some way: you may decide to concede that your opposition has a valid point, or you may wish to refute or counter argue.
Integrate at least eight outside sources (from either scholarly journals and/or databases). These sources will help you explain the context or background for your issue; provide evidence in support of your claim or your counterargument; and represent the oppositional arguments;
Express your informed opinion to help resolve the issue;
Approximately 8-10 pages; 8 sources: Please note the page count does not include the title page, abstract, or the works cited/reference page.
Format and cite sources according to APA or MLA guidelines
A Brief Overview of Argument Strategies:
There are several types of argument essays and strategies that you might want to consider for this assignment. Please note that these strategies can, and are often, combined, though usually writers gravitate toward one overall strategy.
To convince undecided readers to agree with your argument, you would write a classic argument essay: You would support your thesis or claim with reasons and evidence, and address the key oppositional argument(s) with relevant concessions or refutations.
To convince undecided or opposition readers that the opposition’s argument is weak you would write a refutation argument essay: this type of argument essay focuses more on pointing out flaws, problems, weaknesses in the opposition’s argument with evidence, rather than developing one’s own claim/thesis.
To persuade readers that there is a solution or solutions to a problem you would write a problem/solution argument essay: this structure requires you to prove that the problem exists and that your solution(s) would work to fix the problem. You are still required to address opposition and use evidence to support your solution.
I have included the research question in the documents uploaded and you can use whatever writing you find useful in the purpose statement and,problem statement and where I stand.
I also have the citations in the annotated bib that are to be used.
I have included the rubric as well so please follow that as best as you can.
This is an argumentative essay.