The Effects of Huntingon's Disease to the Brain

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Huntington`s Disease
Introduction
Huntington`s illness is a genetic disorder that leads to progressive breakdown of nerve cells in the brain. It adversely affects the patient’s both mental and physical abilities in their life. The disease has no cure, and it is an inherited trait within a family. Quite typically,the disease affects the chromosomes. Nowadays, the disease is at risk of affecting many people in America. It affects people in their adulthood stage from the ages of 25 to 35 years. Besides, it worsens for 10-25 years. The individual succumbs and becomes weak of the diseases leading to other complications such as heart failure or pneumonia. People with HD not only have the genes that develop this disease but also can inherit this gene from their parents (Mestre). Therefore, everyone who possesses the genes will develop the disease later in life.
Amongst the population and the gender distribution, the disease manifests itself differently. Amongst the males, the disease manifests itself way early on in their lives, while amongst the females, it is manifested later on in life. The science keeps an updated record over the emergence of diseases and any gene modification of HD in the world. The symptoms of this disease are neurological and psychiatric since as initially mentioned, it begins at the chromosomal level. Physicians should examine these patients early to provide necessary support and medical services. Frequent checkups help the patients to accept their conditions to avoid harmful activities.
Section 2
Huntington`s disease affects the whole brain leading to malfunction of the brains cells. However, it also affects other areas, which include basal ganglia, cerebral cortex, and striatum to a greater degree. Basal ganglia comprise of a group nuclei significant for movement, emotion, thought, language, and motivation. The cerebral cortex has nuclei responsible for language, thought, perception, and memory (Roos). Besides, basal ganglia control the smooth movement performance of the body muscles. On the other hand, striatum the main factor of basal ganglia. Therefore, these patients have a high risk of brain dysfunction. The patients can also have a trinucleotide repetition disorder that alters the normal body functions.
The cerebral cortex is a region of the brain with the highest level of neural processing. The brain affected by Huntington`s disease will have a total volume of about 20% when a person dies. The brain cells prone to this condition are striatum and cerebral cortex. The body loses the nerve cells of up to 70% and causes the absence of some layers in the brain (Ikezu, and Gendelman 511). A gene mutation found in the fourth chromosome expand its triplet, which repeats itself leading to an unusual version of Huntington protein. The protein aggregates in the nerve cells destroying the brain cells. Some patients change in the involuntary movements of the body and hyper-kinesis.
Section 3
Huntington disorder is a severe aspect interferes with the person`s brain cells. It reduces the number of someone`s nerve cells instead of producing them. They alter the physiological component of a person. They change the experience of the person`s body ...