Clostridium Tetani: Background, Structure, Epidemiology, Treatment, and Prevention

I need microbiology or Biology writer
So I attached three document the first one is example file, the second one is the instruction of the assignment and the third one is the rubric of the assignment. Please let me know if you have any questions. Also make sure you read the entire instruction so you’ll have full idea of the assignment. Thank you so much in advance and let me know if you have any questions

Microbiology For this assignment I am planning to talk about Clostridium tetani 
See below instructions also I will send rubric. Please read all instruction carefully. 
For this assignment, you will take a deeper dive into one specific pathogen that causes human disease.
Pathogenic Microbe Report 
You are training to become a healthcare worker.  In this assignment you will put together a report/write-up of a human pathogen that will help to educate your community and peers about a specific microbe. Your report will teach us all about the pathogen and the disease it causes and inform us about the symptoms, vaccine(s)/tools/behaviors that reduce disease transmission, and what treatments are available.  This assignment is designed to help you apply your epidemiological, structural, pathogenesis, and microbial control knowledge, while practicing scientific communication!
Your finished report will include information on:• Background information and the structure of the pathogen, • the epidemiology and disease(s) caused by the pathogen• information about the vaccine(s), tools, and treatments available (or in development).
Your report must meet the following formatting requirements: • Written in the same order as the topics required in the checklist below (and the rubric).• Written in your own words and properly cited with NO plagiarism.• 2-5 pages (max), double-spaced, 1” margins, Times New Roman font (size 12), paragraph form.• Page limit does not include your name, title, figures, or references (list references starting on a new page).
STEP 1: Prepare• You’ll have the chance to sign up for your pathogen. Sign up ASAP, only one person per microbe.• Each person will work on a single disease-causing organism (virus, bacteria, or eukaryote).• Review the Canvas Module:o Recognizing and Avoiding Plagiarism• Complete the following Canvas Modules:o Evaluating Internet Sources (Highline College Library)o Scholarly vs. Popular Sourceso APA Guide to Citing Sources (7th ed)
STEP 2: Research and Write (Points are in ())
 Reference ALL sources you use! It may help to make an annotated bibliography in a separate document to keep track of your sources while you work!o This includes the CDC websites, WHO websites, your textbook and the pages where you found your information, and any other resources you have chosen to use.  Please write your paper in your own words. I don’t care if you cite 100 sources, if you are looking up information that someone else wrote and including it in your report in any way – CITE THE SOURCE! 
 Most scientific papers don’t use direct quotes! Three or fewer direct quotes are allowed, as long as they are short (<1 sentence, not full sentences), quoted (“in quotations”) and referenced. Using direct quotes usually means you don’t understand what the sentence means, but you think it’s important. If you don’t understand what it means, it’s probably WAY TOO DETAILED for this report!Part 1: Formatting and References (15) in APA format
 (5) Meets formatting requirements for length, spacing, margins, font type, and font size. (5) Cite a minimum of 5 scientific references for your work:o CDC, WHO, Mayo Clinic, original research articles, etc. are great sources for scientific info.o Wikipedia is not a scientific source, but you may find links to good scientific sources and research articles in the footnotes!o Google is not a source – it is a search engine to help you FIND sources.o Cite the original source of photos/figures, not the Google search URL.o For example, your citation for a photo on the lifecycle of a liver fluke SHOULD NOT look like this: https://www.google.com/search?q=liver+fluke+life+cycle&rlz=1C5CHFA_enUS777US778&sxsrf=ACYBGNSW8ZsDaNYeK-w368CXLhVtTcZyRw:1573334040274&source=lnms&tbm= isch&sa=X&ved=0ahUKEwjGkNWEht7lAhVPFjQIHYyZAbgQ_AUIEigB&biwo The photo source is the CDC website: https://www.cdc.gov/parasites/fasciola/biology.htmlo Sometimes Google will find images that are not what you are searching for (i.e. you search for “Varicella zoster virus SEM image”, but MANY other viruses may be pulled up. Make sure you are actually using a photo of the correct organism by going to the original source! (5) References in APA format – A great APA formatting and style guide can be found here (Look on the left side of the page for specifics on formatting in-text citations and references): https://owl.purdue.edu/owl/research_and_citation/apa_style/apa_style_introduction.html o Include in-text (at the end of the sentence) citations in APA format.o Include a separate reference section (at the end of your paper) in APA format.
Part 2: Introduction and Structure of the Pathogen: (30) A short description of the pathogen and its structures 
Identify your pathogen and disease(s) it causes (15) (2) Correctly name the genus and species of your pathogen according to rules found on pg. 12 or Appendix-II, or the NCBI Taxonomy Browser: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi  (1) Is the pathogen a bacterium, virus, single-cellular or multicellular eukaryote (protozoa, fungi, yeast, worm, etc.)? (2) What disease(s) does it cause (give the proper name for the disease). (2) What is the prevalence (where is it common, how many people are infected, die, etc.) (3) What are the common signs and symptoms? (3) Include an electron micrograph or light microscope picture of your pathogen or of one that is similar to it (check with your instructor to make sure it is suitable). Cite your source in APA format right next to the picture!! (1) This section has in-text citations that are properly formatted.
Describe the Structure and features of your pathogen (15) – see below for the requirements for each type:
 If your pathogen is a virus:o (1) What family does the pathogen belong to? (NCBI Taxonomy Browser: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi) o (1) Is it a DNA or RNA virus;o (1) Is it single stranded, or double stranded?o (1) Is it a naked or enveloped virus?o (1) Pathogenesis: what host cells does the virus infect in order to cause disease.o (3) Show a picture and describe the life cycle of the virus. You may use a picture from the book, but you must explain it in your own words and you must cite your source next to the picture.o (6) Hand draw (with a pen/pencil or computer-aided) a picture of this virus. Label and describe the following viral structures if found on your virus and include a summary of their functions:   nucleic acid capsid nucleocapsid spikes matrix envelope (if your pathogen has it) o (1) This section has in-text citations that are properly formatted. If your pathogen is a bacterium: o (1) What family does the pathogen belong to? (NCBI Taxonomy Browser: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi) o (1) Is your bacterium Gram-positive, Gram-negative, acid-fast, or other?o (1) What is the shape of your bacterium (coccus, rod, spiral, fusiform, other?)o (1) Does your organism form endospores? o (1) Where in the body and what type of cells does your bacterium attach to or harm?o (3) Pathogenesis: describe any virulence factors associated with the pathogens which may include any or all of the following:  exotoxins, endotoxins, bacteriophages, plasmids, adherence factors, invasive enzymes/factors, etc.o (6) Hand draw (with a pen/pencil or computer-aided) a picture of this bacterial cell.  Label and describe the following cell structures if found on your organism and include a brief summary of their functions:   cytoplasmic membrane cytoplasm chromosome and plasmid glycocalyx (capsule) if present cell wall (include the layers for Gram + or Gram -) endospores (if your pathogen makes them)  flagella (if present) pili (fimbriae) if present o (1) This section has in-text citations that are properly formatted.
 If your pathogen is a eukaryote:o (1) What family does the pathogen belong to? (NCBI Taxonomy Browser: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi) o (1) What is the shape of your organism?o (1) Does your organism form cysts?o (1) Pathogenesis: Where in the body/what host cells does the organism infect in order to cause disease?o (1) What is the life cycle of your organism? Does it involve other organisms?o (3) Show a picture and describe the life cycle of the organism, including the different forms, and intermediate and definitive/terminal hosts. You may use a picture from the book, but you must explain it in your own words, and you must cite your source next to the picture.o (6) Hand draw (with a pen/pencil or computer-aided) a picture of this organism.  Label and describe the following cell structures if found on your organism and include a brief summary of their functions:   nuclei/organelles flagella/cilia segments outer covering (cuticle, tegument) attachment structures (suckers, hooks, etc.) cysts/oocysts (if your pathogen makes them) Include any other structures relevant to your organism – there’s a huge amount of variability in the shape of eukaryotic pathogens!o (1) This section has in-text citations that are properly formatted.
Part 3: Epidemiology and Treatment (15)Transmission (10) (1) What are the natural reservoirs for the microbe (soil, humans, other animals, etc.)? (1) State whether your pathogen is or isn’t zoonotic. (2) What are the portals of entry AND exit? (specific body parts – name both portals)  (3) How is it transmitted? Include ALL the mechanisms that the pathogen can be transmitted.o indirect transmission (airborne, vehicles, vectors – what are the vehicles/vectors?) o direct transmission (direct contact – how?)o vertical transmission – how?o horizontal transmission – how? (2) Is there anything that makes the host more susceptible (age, disease, immunocompromised, etc.)? (1) This section has in-text citations that are properly formatted.
Treatment (5) (2) How is it treated if someone has the disease? (1) Is one or more antibiotic, antiviral, antiprotozoal/antifungal/anthelmintic used? What is/are the name of the drug(s)?  (1) How does the drug target/affect the pathogen (the mechanism of the drug)? If no treatment is available, describe how an antibiotic/antiviral could be used to target this type of pathogen. (1) This section has in-text citations that are properly formatted.Part 4: Prevention:  Reducing disease transmission (10)
 (4) Briefly describe how to decrease the transmission of your disease (think of the mechanism of transmission, not just vaccination – diseases have been around longer than vaccines!!)
 (4) Is there a vaccine(s) that protects against this microbe? o If so, how is it made (killed whole microbe, live-attenuated, inactivated toxin (toxoid), subunits of the microbe, recombinant)?  Check out: https://www.cdc.gov/vaccines/pubs/pinkbook/index.htmlORo If a vaccine is NOT currently available, are there any in development? What stage of development is it in, or what are the issues faced with developing a vaccine for this disease? What kind of vaccine in the “pipeline” shows promise? You may have to dig for this information in the links: https://www.cdc.gov/vaccines/vpd/vaccines-list.html https://www.who.int/immunization/diseases/en/ (1) This section has in-text citations that are properly formatted.
STEP 3: Submit your DRAFT
 (30) Your report is mostly complete, meets the criteria in the categories above, including properly citing (not plagiarizing) your sources!o submit as ONE .doc, .docx, or .pdf file
STEP 4: Complete Two Peer Reviews
 (20) Complete the reviews of TWO of your peer’s draftso You will be randomly assigned an anonymous peer’s draft to review using a rubric and providing feedback comments on their draft.o NOTE: You will need to access the peer review from a computer, not through the Canvas app!
STEP 5: Submit Your FINAL Report
 Review the feedback from your peer and incorporate edits into your final report. Review the formatting and source citation requirements. Submit your final report.