Concepts of Foundational Neuroscience Applied to Psychiatric Mental Health Nurse Practitioner
Discussion question ( It should be more than 275 words. It should be a full-page please.) Thanks
Reflect on the concepts of foundational neuroscience as they might apply to your role as the psychiatric mental health nurse practitioner in prescribing medications for patients.
1. Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.
2. Compare and contrast the actions of g couple proteins and ion gated channels.
3. Explain how the role of epigenetics may contribute to pharmacologic action.
4. Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.
Neurotransmitters and Receptor Theory
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Question One: Agonist/Antagonist
Any drug or medication that triggers and causes an activation on the brain's receptors to cause a drug's full effect is known as an agonist (Bell & Strang, 2020). On the other hand, an antagonist is any drug or medication that works by blocking brain receptors from binding to the agonist. A partial agonist is a drug or medication that behaves like an agonist, with reduced activation of the receptors (Bell & Strang, 2020). Partial and inverse agonists are used to lower and reverse the effect of harmful agonists such as Heroin.
Question Two: Ion Gated Channels/G-Couple Proteins
G-couple proteins (GCPs) and Ion Gated Channels (IGCs) are classified under postsynaptic receptors (Badheka et al., 2017). IGCs act by binding neurotransmitters and forming ion channels. On the other hand, the G-protein-coupled receptors (GPCRs) operate through second messenger systems that are usually slow and reliant on metabolic actions (Badheka et al., 2017).
Question Three: Epigenetics
The function of genes can be changed or modified w...
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