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Subject:
Life Sciences
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Essay
Language:
English (U.S.)
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Topic:

What new research questions does the paper address?

Essay Instructions:

the original research paper referred to in the article is " The survival gene MED4 explains low penetrance retinoblastoma in patients with large RB1 deletion" website: https://academic(dot)oup(dot)com/hmg/article/23/19/5243/2900957
please use AMA style citation as mentioned in my assignments.
please number the answers for each question (not in essay form)
please read the instructions carefully, thank you so much!

Essay Sample Content Preview:

Title: Name: Degrees: Email Address: Institution Affiliation
1. What is the title of the research paper that news article are referring to? Provide a complete reference indicating the authors, date of publication, and journal. Dehainault, C., Garancha, A., Castera, L., Cassoux, N., Aert, I., Doz,F., Desjandis, L., Lumbroso, F., Rocio Montes de Oca, &Almouzni, G. The survival gene MED4 explains loe penetrate retinoblastoma in patients with large RB1 deletion. Human Molecule Genetics. 2014, 23, issue, 19, 5243-5250.https:doi.org/10.1093/hmg/ddu245. Accessed 23 May 2014.2. What new research questions does the paper address?   The research question states why patients with large deletion in retina experience the low penetrance. The question is significant because through the analysis it was discovered that RB Rb1-/- cells could not survive without MED4; thus, MED4 plays a critical role in the complex.13. What is MED4 and what is its role in cellular level? MED4 is a subunit of the mediator complex, and it is the survival gene in the retinoblastoma.14.  Briefly explain how did they determine that MED4 is responsible for low pe...
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