Summarize: This is a Meta-Analysis and a Systematic Review

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1 Anderson, L., Nuckols, T., Smith-Spangler, C., Morton, S., Deichsel, E., Asch, S., Patel, V., … Shekelle, P. (June 04, 2014). The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis. Systematic Reviews, 3, 1, 1-12.
This is a meta-analysis and a systematic review of a number of articles that sought to compare computerized provider order entry (CPOE) with paper-order entry in acute care hospitals as well as diverse preventable adverse drug events (pADEs) or medication errors. This meta-analysis utilized articles drawn from several sources including MEDLINE, Cochrane Library, Econlit, web-based databases, and bibliographies of previous systematic reviews (as at September 2013). Sixteen (16) studies of the studies analyzed addressed medication errors while six addressed pADEs. The results indicated that CPOE was associated with half as many pADEs (pooled risk ratio [RR] = 0.47, 95% CI 0.37 to 0.71) and medication errors (RR = 0.46, 95% CI 0.35 to 0.60) compared to paper-order entry. Regarding diversity effects on medication errors, two contextual and five intervention factors were satisfactorily reported to support subgroup meta-regression or analyses. Despite their favorable results on CPOE implementation, the meta-analysis utilized a weak study design (pre-post design) that does not have control over other elements that might be changing at the same time as the intervention (CPOE) is implemented.
2 Radley, D.C., Wasserman, M.R., Olsho, L.E.W., Shoemaker, S.J., Spranca, M.D., & Brashaw, B. (2013). Reduction in medication errors in hospitals due to adoption of computerized provider order entry systems. DOI: http://dx.doi.org/10.1136/amiajnl-2012-001241 470-4...