Lurasidone Hydrochloride: Latuda is an Antipsychotic Drug

Lurasidone Hydrochloride: Latuda is an Antipsychotic Drug 
Lurasidone given in health facilities and sold in pharmacies as Latuda is an antipsychotic drug utilized to manage and handle bipolar disorder, a mental illness that causes inappropriate emotions, loss of interest in life, and unusual thinking (Lurasidone, 2018). Bipolar disorder is a depressive disorder that leads to episodes of mania and depression, and schizophrenia disorder. The generic name for the medication is lurasidone hydrochloride, while its brand name is latuda. 04507230(Lurasidone, 2018).(Lurasidone, 2018).01754505The Food and Drug Administration (FDA) outlines in its Drug labeling information that Latuda should be prescribed for children between 13 and 17 years old and adults with schizophrenia. In addition, it is recommended monotherapy treatment for adults with bipolar disorder. Patients use Lurasidone with Depacon (valproate) and Lithobid (lithium) to manage the disorders.
Lurasidone medication is categorized under atypical antipsychotic drugs responsible for altering the functioning of particular substances in the brain. The drug is a complete antagonist of serotonin 5-HT2A, 5-HT7, and dopamine D2. The drug functions by blocking receptors of dopamine neurotransmitters, noradrenaline, and 5-hydroxytryptamine, thus regulating and normalizing the rapid activity of the brain hence reducing the bipolar disorder symptoms. Regarding the drug pharmacokinetics, it is metabolized through CYP3A4 (Lurasidone, 2018). It involves biotransformation pathways that enable the drug to be metabolized into two active metabolites, ID-14326 and ID -14283, and two non-active metabolites, ID- 20220 and ID-20219. Due to Latuda not being a substrate of CYP1A2, smoking individuals with bipolar disorder or schizophrenia are not affected by the pharmacokinetics of Lurasidone. Moreover, the medication is absorbed in the patient’s body, reaching serum concentration peaks between one and three hours of intake. About 9-19 % of Latuda taken is absorbed in the body.
The medication’s pharmacodynamics are mostly absorbed in the liver through isoenzyme 3a4 and cytochrome P450 (Latuda, 2021). Excretion radioactivity resulting from the drug in feces and urine is measured at 89%. This implies that CV% clearance was 18ml after administration of 40mg of Lurasidone.
Administration of Lurasidone
The recommended dosage of Lurasidone for patients is 37 mg a day. For any dose increases, a physician should be first consulted. For patients who have bipolar disorder, Latuda can be combined with lithium and valproate drugs. For this particular condition, 20 mg should be administered daily for young adults (Latuda, 2021). For grown-up adults, 20 mg to 80 mg dosage can be administered. Pregnant women should take a maximum of 10mg a day, while for elderly 03272155(Latuda, 2021).(Latuda, 2021).01748790adults, it i...