Epidemiology and EBP Guidelines on Thalassemia and Sickle-Cell Anemia

Thalassemia and Sickle-Cell Anemia
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Thalassemia and Sickle-Cell Anemia
Thalassemia
Thalassemia is a common disorder that reduces normal hemoglobin in the body. Hemoglobin determines how the red blood cells carry oxygen. Thalassemia is a vital condition since it may cause anemia (Viprakasit & Ekwattanakit, 2018). Thalassemia limits hemoglobin chains, thus destroying the red blood cells. It manifests in different ways, including erythropoiesis or hemolytic anemia. Thalassemia requires a well-established diagnosis by conducting specific blood tests and taking a medical history from the family to identify whether an individual suffered the same problem in the family line. The chronic management of the disorder requires evidence-based guidelines based on modern treatments. The treatments include iron chelation. The health expert should conduct iron chelation either orally or using a subcutaneous intravenous approach. The health experts can also take the patients through splenectomy instead of blood transfusion. Lastly, other interventions also feasible in addressing the condition include cell transplantation and transplant...