Process Integration and Control: Achieving Continuous Bioprocessing

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Process Integration and Control
The issue of continuous bioprocessing is tackled by the article. It provides essential information to understand which factors should be modulated in order to achieve continuous bioprocessing. Developing technologies provide opportunities for improvement of the ways of bio processing. The article shares that bioprocessing has been always done by batch, and that recent discoveries in the different fields of science has unlocked a critical component which will enable continuous bioprocessing.
The research mentions 3 approaches about the topic. The major methodology of the proposed framework for continuous bioprocessing revolves around modular approach. This method would allow worn parts to be easily replaced, while allowing efficiency of the different process involved in the biomaterial production. The adaptation approach meant that units of operations are modified in order to create a continuous and faster cycle. This also meant the seamless integration of the operating units with each other. The field of biopharmaceutical manufacturing has seen a wide array of benefits for humanity and the scientific field. The specificity of bioavailable materials has been understood by science, thereby giving people the capability to produce biomaterials at the desired parameters. The article mentions 2 devices that are relevant for continuous bioprocessing. These 2 devices can be used in modular set-up such as the ATF or Alternating Tangential Filtration, and the AWS or Acoustic Wave separators. These devices provide essential factors that allow certain molecules to be extracted.
A major take away that I have from the article is the Diafiltration process. Thi...