Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants

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June 21, 2020
Randomized Trial of Introduction of Allergenic Foods In Breast-Fed Infants
Perkin, M., Logan, K., Tseng, A., Raji, B., Ayis, S., Peacock, J., Brough, H., Marrs, T., Radulovic, S., Craven, J., Flohr, C., & Lack, G. (2016). Randomized trial of introduction of allergenic foods in breast-fed infants. New England Journal of Medicine, 374, 1733-1743. https://doi.org/10.1056/nejmoa1514210
The purpose of this randomized, controlled study was to examine the effect of early introduction of allergenic foods on the protection of breast-fed infants against allergic reactions due to food. Inclusion criteria were breastfeeding babies aged 3 months and given allergenic foods who comprised of the early-introduction group (EG) and exclusively-breastfed babies up to 6 months forming the standard-introduction group (SG). Exclusion criteria included an age of 3 months for both the SG and the EG. Babies aged 3 months and exclusively given breast milk were recruited and enrolled in a 3-year study. Participants were randomized and grouped to either the EG or the SG. Parents to infants in the EG with positive results after the introduction of allergenic foods at baseline were advised to stop giving their babies that specific food but instead continue giving the infants other ...