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Pages:
1 page/β‰ˆ275 words
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APA
Subject:
Health, Medicine, Nursing
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English (U.S.)
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Topic:

Treating and Managing Seizures

Other (Not Listed) Instructions:

read the following paper from my college and response in one or more of the following ways:
Ask a probing question, substantiated with additional background information, evidence, or research.
Share an insight from having read the below postings, synthesizing the information to provide new perspectives.
Offer and support an alternative perspective using readings from the classroom and/or from your own research in the university library.
Cite a minimum of three credible sources
Due to the treatment failure of Dilantin, and its subsequent discontinuation in favor of lamotrigine, the prescriber fulfilled their major responsibility of monitoring the frequency and severity of seizures, adverse drug events, and plasma drug levels of Molly (Arcangelo, 2022). Dilantin, or phenytoin, works primarily by blocking sodium channels in the brain whose membranes are highly voltage dependent. In doing so, the action potential is decreased, and the positive feedback is blocked from high-frequency, repetitive firing of neurons associated in seizure activity (Gupta, 2022). Due to the daily use, and narrow therapeutic window, Molly’s prescriber decided correctly to discontinue the Dilantin, to decrease the likelihood of toxicity (Iorga, 2022). In its stead, the prescriber chose to start Molly on lamotrigine, or Lamictal, which is another first-line treatment option for seizures, rather than opting for a second-line treatment (Arcangelo, 2022). This follows the algorithm for epilepsy treatment outlined in the Arcangelo text (2022). The mechanism of action for Lamictal, unlike Dilantin, is not fully understood, but appears to act on glutamate to stabilize neuronal membranes, and inhibit voltage-sensitive sodium channels (Arcangelo, 2022; Betchel et al., 2022).
Because Molly is sexually active, the practitioner will need to be explicit with providing health-teaching regarding Molly’s epilepsy medications. Regardless of the medication, “women taking anticonvulsant therapy, a major point for discussion is the risk during pregnancy,” (Arcangelo, 2022). Had Molly stayed on Dilantin, she would need to use caution in regards to pregnancy, as it is a category D medication (Arcangelo, 2022). This means there is a greater risk for fetal abnormalities (Arcangelo, 2022). Since Molly was switched to Lamictal, she will still need to exercise caution. Lamictal, as well as other antiepileptic medications can decrease serum concentrations of progestins (Arcangelo, 2022). If Molly is taking an oral contraceptive, this decrease in progestins can lead to a failure of the oral contraceptive (Arcangelo, 2022).
References:
Arcangelo, V. P. (2022). Pharmacotherapeutics for advanced practice: A practical approach. Wolters Kluwer.
Betchel NT, Fariba KA, Saadabadi A. (2022). Lamotrigine. In StatPearls. StatPearls Publishing.
Gupta M, Tripp J. (2022). Phenytoin. In StatPearls. StatPearls Publishing.
Iorga, A., & Horowitz, B. Z. (2022). Phenytoin Toxicity. In StatPearls. StatPearls Publishing.

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Response 2 Seizure
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Response 2 Seizure
Are there highly effective contraceptives for women with epileptic that Molly can consider rather than taking chances with oral ones whose effectiveness remains in doubt due to interactions with antiepileptic medications?
Your discussion demonstrates that antiepileptic drugs such as Dilantin, Lamotrigine, and many others provide congenital risks for pregnant women. The revelation that their action interferes with the effectiveness of contraceptives triggers a worry that a patient like Molly could become pregnant and expose her unborn child to diverse complications. Since Molly requires her medications to control her seizure episodes, yet she remains sexually active, finding a more reliable approach for preventing conception offers the best solution in her care management. However, the concern is whether any approaches can assure her absolute effectiveness.
Studies exploring this issue provide several propositions that patients in Molly’s situation can embrace to improve their health outcomes. For instance, Herzog et al. (2019) indicate that healthcare providers should recommend contraceptives categorized as highly effective because they have a lesser than 10% annual failure rate. Such approaches include IUDs, vasectomy, and tubal ligation. Noe (2019) supports this approach by confirming that these options improve the patient’s capacity to con...
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