Microbiology

Microbiology
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Microbial infection in an organism leads to tissue damage. This occurs through various mechanisms but in whichever way with the microbial infection there is bound to be tissue infection. This occurs through various graft destruction through the various mechanisms. If the microbial organism has tropism for the graft, there is bound to be occurrence of direct cytopathic. This leads to release of damage associated molecular patterns as well as microbial or donor antigens also known as alloantigen (Cox, Simpson, Letts, & Cavanagh, 2014). These cause tissue damage. Again, the presence of the microbial organisms results to augmentation of direct activation of alloactive T cells by enhancing maturation of donor APCs or graft parenchymal cells. This process results to graft damage. The repeated process causes damage of the tissue of the organism which has been infected by the microbial organisms.
Control of the growth of the microbes or total elimination is crucial in the prevention of infections. The efforts include deliberations to curb the growth of the microbial or the total elimination. One process that has been highly adopted in sterilization is the heat method. When the heat method is selected as the preferred method of sterilization; it is crucial that the essential factors are considered. These are the type of heat to be used. This highly depends with the available type as well as the most convenient if there is a variety of sources to choose from. (Cox, Simpson, Letts, & Cavanagh, 2014) Time of the application of the temperature must also be considered. The applied temperature must also be keenly selected especially in relation to the load involved in the sterilization. High temperature ensures killing of the microbial organisms. When the temperature is high, there is rapid killing of the microbial organisms. This is unlike low temperatures which; although they may still end up eliminating the microbial organisms, it may take too long. Autoclaving is a common method of sterilization that is based on heating. Here temperature is applied in relation to the time.
This is also highly depended with the load to be sterilized. If the load to be sterilized is huge, then it means that the temperature should be higher and the process should also take longer time. This ensures complete elimination of the microbes because they are unable to survive in those very high temperatures. This method of using heat to eliminate the microbe or rather in sterilization is very much preferred in the scientific deliberations due to the convenience that come with it. Unlike the usage of chemicals, this process of sterilization is not harmful to the environment. Again, it is relatively cheap in consideration of the required materials. Again, it does not require so many technicalities. The process is simple such that with little instructions, one can accomplish the process. (Gertner, 2015)It is therefore a very safe method, except in consideration of the dangers associated with the heat, which is very effective in the elimination of the microbes. This is because; as long as one utilizes the required temperature, one can be sure of the total elimination of the microbes.
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