Sign In
Not register? Register Now!
Essay Available:
Pages:
1 page/β‰ˆ275 words
Sources:
3 Sources
Style:
APA
Subject:
Health, Medicine, Nursing
Type:
Research Paper
Language:
English (U.S.)
Document:
MS Word
Date:
Total cost:
$ 5.83
Topic:

The Agonist-to-Antagonist Spectrum of Action of Psychopharmacologic

Research Paper Instructions:

Week 2: Neurotransmitters and Receptor Theory

Receptors and neurotransmitters are like a lock-and-key system. Just as it takes the right key to open a specific lock, it takes the right neurotransmitter to bind to a specific receptor. Not surprisingly, as it concerns psychopharmacology, the pharmacotherapeutics that are prescribed must trigger the release of certain neurotransmitters that bind to the correct receptors in order to elicit a favorable response for the patient. The mechanism of this binding and the response that follows reflects receptor theory and lies at the foundation of pharmacology.

This week, you will continue your examination of neuroanatomy and neuroscience as you engage with you colleagues in a Discussion. You will also explore the potential impacts of foundational neuroscience on the prescription of pharmacotherapeutics.

Learning Objectives

Students will:

  • Analyze the agonist-to-antagonist spectrum of action of psychopharmacologic agents
  • Compare the actions of g couple proteins to ion gated channels
  • Analyze the role of epigenetics in pharmacologic action
  • Analyze the impact of foundational neuroscience on the prescription of medications

Learning Resources

Required Readings (click to expand/reduce)

 

Required Media (click to expand/reduce)

 

Optional Resources (click to expand/reduce)

 

Discussion: Foundational Neuroscience

As a psychiatric and mental health nurse practitioner, it is essential for you to have a strong background in foundational neuroscience. In order to diagnose and treat patients, you must not only understand the pathophysiology of psychiatric disorders but also how medications for these disorders impact the central nervous system. These concepts of foundational neuroscience can be challenging to understand. Therefore, this Discussion is designed to encourage you to think through these concepts, develop a rationale for your thinking, and deepen your understanding by interacting with your colleagues.

 

Photo Credit: Getty Images/Cultura RF

For this Discussion, review the Learning Resources and reflect on the concepts of foundational neuroscience as they might apply to your role as the psychiatric mental health nurse practitioner in prescribing medications for patients. 

By Day 3 of Week 2

Post a response to each of the following:

  1. Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.
  2. Compare and contrast the actions of g couple proteins and ion gated channels.
  3. Explain how the role of epigenetics may contribute to pharmacologic action.
  4. Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.
Research Paper Sample Content Preview:
The Agonist-to-Antagonist Spectrum of Action of Psychopharmacologic
1 Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.
There are two psychopharmacological substances: those that function as an agonist and those that act as an antagonist. A biological response can be elicited by agonists, which bind to receptors and activate them. Even though an antagonist inhibits the impact of an agonist and an inverse antagonist causes an action that is directly in opposition to the agonist's, there is a distinction between an antagonist and an inverse antagonist (Stahl, 2013). There are four main types of agonists: agonist, antagonist, and inverse agonist. However, when it comes to antagonists, they do not leave their resting state as frequently as their agonist counterparts, and they activate the channel less regularly. When an inverse agonist is present, ion channels are shut down and blocked.
2 Compare and contrast the actions of g couple proteins and ion gated channels.
The ion channels in postsynaptic membranes are opened and closed by two distinct types of receptor proteins. Cellular ion channels and receptors such as the ionotropic receptor are inseparably linked. Neurotransmitter-binding extracellular domains and membrane-spanning ion channels are given to these receptors' two functional parts (Purves et al., 2012). Inotropic receptors are also known as ligand-gated ion channels. Molecular entities called inotropic receptors to combine transmitter binding and channel action into a single unit. Because they include four or five different subunits, these receptors are called multimers. Although these receptors lack ion channels, activation of intermediary molecules known as G-proteins can still influence the channels. Because of this, G-protein-coupled receptors are commonly referred to as G-protein-coupled receptors.
3 Explain how the role of epigenetics may contribute to pharmacologic action.
Studying how environmental v...
Updated on
Get the Whole Paper!
Not exactly what you need?
Do you need a custom essay? Order right now:
Order

πŸ‘€ Other Visitors are Viewing These APA Research Paper Samples:

HIRE A WRITER FROM $11.95 / PAGE
ORDER WITH 15% DISCOUNT!
Order Now