Osteoporosis, Osteomalacia, Rheumatoid Arthritis, Gout, and Osteoarthritis

Bone Disease
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Bone Disease

Disease

Pathophysiology

1

Osteoporosis

It is skeletal fragility, a disorder that results in decreased bone mass. There is a higher risk of fracture when the bone's tissues deteriorate. The World Health Organization finds categorizing adult males with a bone mass of less than 2.5 (Capriotti, 2020) is beneficial. As a result, They become more frail, making them more susceptible to vascular diseases like hypertension.

2

Osteomalacia

The matrix of the bones is unchanged; however, there is a mineral shortage. A lack of certain enzymes that reduce vitamin D production is one of its causes. Less phosphorus is absorbed as a result of the factors mentioned above. Additionally, anticonvulsants reduce the absorption of these minerals. Osteomalacia is a condition that is very common in patients who are kept inside.

3

Rheumatoid Arthritis

A persistent inflammation impacts the connective tissue around the joints and the joints themselves. It primarily affects older people between 35 and 50 (Capriotti, 2020). In men, it is more severe. It is initially minor and may become chronic, resulting in deformity or disability.

4

Gout

It responds to monosodium urate, which may be found in soft tissue, joints, or bones. It may be a side effect of arthritis, either slight or chronic.

5

Osteoarthritis

It is the damage of articular cartilage over time. The bone that lies beneath the articular cartilage changes shape as a result. Both impairment and discomfort are brought on by it. It results from a reaction to the chondrocytes present in the articular cartilage.


Disease

Etiology

1

Osteoporosis