Structural Abnormalities Seen in Patients with Schizophrenia
QUESTION 4
Scenario 1: Schizophrenia
A 22-year-old female student was brought to her college student health department by her boyfriend. He was concerned about the changes in her behavior. The boyfriend noted that she has been hearing voices, and seeing things that are not there. She also thinks that there are people that want to harm her. She told her family that she cannot finish college as the voices told her to quit because she is “dumb”. The boyfriend relates episodes of unexpected rage and crying.
PMH: noncontributory
FH: positive for a first cousin who “had mental problems”.
SH: Denies current drug abuse but states he smoked marijuana every day during junior and senior years of high school. Admits to drinking heavily on weekends at various fraternity houses.
PE: thin, anxious disheveled female who, during conversations, stops talking, tilts her head and appears to be listening to something. There is poor eye contact and conversation is disjointed.
DIAGOSIS: schizophrenia.
Questions:
Explain what structural abnormalities are seen in people with schizophrenia.
Concepts of Psychological Disorders
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Structural Abnormalities Seen in Patients with Schizophrenia
Schizophrenia results in changes in the brain, including the structure of specific brain systems and their functioning mechanism. The areas of the brain that are usually affected include the medial temporal lobe and the prefrontal lobe (Kochunov et al., 2017). These areas of the brain are involved in ensuring a declarative memory and a working memory, respectively—the cortex experiences bold changes in schizophrenia that are both structural and functional. The use of neuroimaging technology aids in viewing the changes. Some of the structural abnormalities observed include a decline in the volume of the gray matter and a reduction in the integrity of the white matter (Palaniyappan, 2017). These abnormalities usually progress rapidly before the onset of the disease and during the initial onset stages of the disease.
In addition to the structural abnormalities observed in the gray matter in people with schizophrenia, some changes occur in the white matter. The integrity of the white matter is disrupted. The abnormalities can be seen through neuroimaging in new schizophrenic and chronic patients (Wolfers et al., 2018). The volume of the white m...
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