Pathophysiology of Clotting Cascade
Note, Disease to write on is Clotting Cascade . References should be between 5, And if you list a reference make sure to have the citation too--- check out owl.purdue.edu -- must have both.
Learning Objectives
Students will:
Analyze concepts and principles of pathophysiology across the lifespan
In this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.
The circulatory system and the respiratory system are powerful partners in health. While they work closely together in good health, a disease or disorder that manifests in one can have a significant impact on both, hampering the pair’s ability to collaborate.
Cardiovascular and respiratory disease and disorders are among the most common reasons for hospital visits, and among the leading causes of fatality. Heart disease and pneumonias are among the most familiar, but a wide variety of issues can impact physiological functioning of one or both systems.
This week, you examine fundamental concepts of cardiovascular and respiratory disorders. You explore common diseases and disorders that impact these systems, and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients
Concepts of Cardiovascular and Respiratory Disorders (Clotting Cascade)
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Clotting Cascade
The clotting cascade is closely related to the concept of coagulation. It is a term used to explain the biological and chemical underpinnings underlying the occurrence of coagulation (Ong et al., 2018). In clotting cascade, fibrinogen is cleaved by thrombin leading to the formation of an insoluble substance that is otherwise known as a blood clot (Barmore et al., 2019). This process is activated in a situation where a blood vessel has been damaged, and there is blood loss. Consequently, a clotting cascade is a normal response towards a damaged blood vessel.
Whereas the process largely occurs to prevent blood loss, some abnormal conditions may lead to an undesirable clotting cascade (Napeñas & Patton, 2021). Just like with the concept of coagulation, this undesirable process would lead to the blockage of a blood vessel(s). A clot would reduce blood flow (McCance & Huether, 2019). Such an occurrence would directly affect the cardiovascular and respiratory systems. For the cardiovascular system, a blood vesse...
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