Selecting source of literature

Selecting Sources of Literature
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Selecting Sources of Literature
For this research, the identified problem is adults with total knee replacement (TKR) and the proposed solution is low-molecular-weight heparin, also known as nadroparin, in preventing deep-vein thrombosis (DVT) after TKR. The PICOT question is: in adults who have undergone TKR (P), Nadroparin (I) is more effective than other therapies such as mechanical prophylaxis (C) in preventing deep-vein thrombosis (O). In this paper, 15 peer-reviewed articles that describe the problem and that support the proposed solution are described.
Article 1: Giannoni, M. F., Ciatti, R., Capaccia, L., Ruggiero, M., Dauri, M., & Mariani, P. P (2009). Total Knee Replacement: Prevention of Deep-Vein Thrombosis Using Pharmacological (Low-Molecular-Weight Heparin) and Mechanical (Intermittent Foot Sole Pump System) Combined Prophylaxis. Preliminary Results.
This article is research-based. In their study, the Giannoni et al (2009) sought to determine the role of combined pharmacological and mechanical prophylaxis in preventing deep venous thrombosis following total knee replacement. The design was prospective case series study. Thirty-eight total knee procedures were performed on 34 patients, and four patients had bilateral TKR. Patients were given injection of nadroparin calcium and observed for 15 days. Their findings showed that nadroparin calcium greatly reduced the occurrence of DVT implying that it is effective in preventing DVT infections after TKR.
Article 2: Blanchard, Y., Meuwly, P., Leyvraz, M., Miron., Bounameaux, H., Hoffmeyer, P., Didier, D., & Schneider, P. (2010). Prevention of Deep-Vein Thrombosis after Total Knee Replacement. The Journal of Bone and Joint Surgery.
This article is research-based. Total Knee Arthroplasty (TKA) is linked to a major risk of getting DVT, as well as pulmonary embolism. The incidence of total deep-vein...