Dopamine and its Effects in the Human Body
1.Introduce Dopamine, How they discover dopamine? When they discover it? who discover it? where they discover it? 2.What is Dopamine? How Dopamine affect human behavior? How can we use the effect of Dopamine in a positive way? How they first use the benefit of Dopamine? Illustrated the advantages and disadvantages of dopamine? 3.Where Dopamine produce?Is there a normal value of dopamine in the human body?What happen if you are depleted with dopamine? What happen if you are too much of Dopamine?Please illustrate personal scenario. 4.What is Dopamine function?How they works and benefit human being? 5.How it is useful and not useful give personal experience? 6.What diseases associated from too much and too little of Dopamine? what are the test to determine dopamine level? What are the signs and symptoms of too much and too little dopamine? 7.How can you treat dopamine diseases? statistics mortality rate?
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Dopamine and its Effects in the Human Body
Introduction
Dopamine is a neurotransmitter chemical secreted in the brain, and it regulates physiological and motor control functions such as emotion, mood, appetite, pain, pleasure, and body movement. It is an amine compound, which is derived from ammonia. An increase in the amount of dopamine in the brain accelerates neural activity, which results in excitement, pleasure seeking behavior (such as sexual arousal), as well as physical activity (hyperactivity). Its action is similar to adrenaline because it is a chemical messenger that speeds up cell activity.
Discovery
The chemical dopamine was first discovered by the Swiss pharmacologist Arvid Carlsson in 1952. However, it was not until five years later, in 1957, while working at the Pharmacology Department in Sölvegatan, Lund, that Carlsson discovered the chemical’s neurotransmission properties (Christine and Aminoff 412). This discovery refuted previous assumptions by scientists that dopamine was a catalyst for adrenaline release, and not a neurotransmitter in its own right.
How Dopamine’s Neurotransmission Function Was Discovered
The chemical was discovered when Carlsson and his coworkers observed that the akinetic effects of reserpine, an alkaloid used to treat severe agitation in persons with mental disorders, can be reversed by administering a dose of the dopamine. The reversal effect on reserpine was correlated to the restoration of dopamine levels in the brain. This suggested that it was the depletion of dopamine, and not serotonin or noradrenaline as previously thought, that caused akinetic effects in animals treated with reserpine. In 1958, two of Carlsson’s students discovered that there was high concentration of dopamine in striatum, a part of the brain that contains minimal noradrenaline supply and is associated with motor control. This knowledge led to the conclusion that dopamine played a major role in motor-function control.
Normal Body Value of Dopamine
The normal levels of dopa...
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