Medically Useful Antibiotics Against Peptidoglycan Synthesis

2. Most medically useful antibiotics interfere with either peptidoglycan synthesis or
ribosome function. Why would the cytoplasmic membrane be a poor target for
antibacterial medications?
3. You are a microbiologist working for a pharmaceutical company and discover a new
metabolite that can serve as a medication. You now must oversee its production. What
are some factors you must consider if you need to grow 5,000-liter cultures of bacteria?
One page per each question and make sure to add cited works used. please

Take-home Project 1 (MICR2330, Fall 2020) (Due on October 2, 2020, Friday) Please read textbook or other literature to write a mini-review paper (at least one page for each question) to address below questions. When you cite literature in your paper, please put the cited reference into your paper. (10 points for each question, total 50 points) Your papers must be typed and double-spaced. No hand written papers will be accepted. Later papers will receive a 10% deduction in points for each day (including non-class days) they are late. You can email your assignment to me with an attachment (my UTEP email: [email protected]). Questions: 1. Why is the study of bacteria important? Please list the important benefits of microorganisms. 2. Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cytoplasmic membrane be a poor target for antibacterial medications? 3. You are a microbiologist working for a pharmaceutical company and discover a new metabolite that can serve as a medication. You now must oversee its production. What are some factors you must consider if you need to grow 5,000-liter cultures of bacteria? 4. Just before winter break in early December, your roommate stocks the refrigerator with a gallon of milk, but both of you leave before opening it. When you return in January, the milk has soured. Your roommate is annoyed because the milk was pasteurized and thus should not have spoiled. (1) Explain why your roommate’s position is unreasonable? (2) Design an experiment to prove that microbes do not spontaneously generate in milk? 5. As we know, Dr. Barbara McClintock (1902-1992) was a famous scientist who made several very important discoveries in genetics, and she received a Nobel Prize for her discovery of transposons, popularly called “jumping genes”. If you were asked to nominate her for the Nobel Prize, please search the internet and literatures, then make a statement supporting your choice.