Essay Available:
Pages:
1 page/β275 words
Sources:
1 Source
Style:
Other
Subject:
Biological & Biomedical Sciences
Type:
Lab Report
Language:
English (U.S.)
Document:
MS Word
Date:
Total cost:
$ 4.32
Topic:
12.2 Research Assignment: Chronic Myeloid Leukemia
Lab Report Instructions:
12.2 Research Assignment: Chronic Myeloid Leukemia
Lab Report Sample Content Preview:
Chronic Myeloid Leukemia
Name:
Institution:
Course:
Date:
Chronic Myeloid Leukemia
Protein kinases are enzymes that chemically add phosphate groups to other proteins with the aim of modifying them (Howard Hughes Medical Institute, 2017). This means that even the protein which are changed will result in functional changes, associated with the way they interact with other proteins, their cellular location and enzymes.
The facilitation of the phosphorylation processes is made possible through the donation of the phosphate molecule which comes from the adenosine triphosphate (ATP), which is a universal donor for Phosphoryl (Howard Hughes Medical Institute, 2017).
The BCR-ABL kinase is caused by genetic mutations that result in the development of chronic myeloid leukemia.
Between the BCR-ABL and the ABL, the two have different binding sites. This is relative to the fact that they have been modified differently; this is with reference to the BCR-ABL due to mutations.
Every other cell in a human body has 23 pairs of chromosomes. During translocation of the chromosomal material some parts of the chromosome 22 goes to 9 and the vice versa. This then results in a shorter chromosome 22. This leads to the formation of a new gene that is generally referred to as the BCR-ABL an oncogene. It is this gene that then causes the cancer cells, CML (Howard Hughes Medical Institute, 2017).
The drug developed by scientists to treat CML was referred to as Gleevec.
This is a drug that works by blocking the binding cites for the BCL-ABL and the prevents the unregulated activity.
Some of the patients developed resistance after long use, this is relative to the fac...
Get the Whole Paper!
Not exactly what you need?
Do you need a custom essay? Order right now:
π Other Visitors are Viewing These Other Lab Report Samples:
- Assignment 11.1: Biotechnology, Immune System, Diagnostic1 page/β275 words | 1 Source | Other | Biological & Biomedical Sciences | Lab Report |
- Lab Report On Effect Of Restriction Enzyme On Dna Piece2 pages/β550 words | 1 Source | Other | Biological & Biomedical Sciences | Lab Report |
- Bacterial Identification Virtual Lab: A Lab Report1 page/β550 words | 1 Source | Other | Biological & Biomedical Sciences | Lab Report |
- Writing Assignemnt Paper 10.2: DNA Fingerprinting1 page/β550 words | 1 Source | Other | Biological & Biomedical Sciences | Lab Report |
- Howard Hughes Medical Institute Institute the ELISA1 page/β550 words | 1 Source | Other | Biological & Biomedical Sciences | Lab Report |
- Familiarizing the Microscope2 pages/β550 words | Other | Biological & Biomedical Sciences | Lab Report |
- Photosynthesis Laboratory Questions Biological Sciences Lab Report2 pages/β550 words | Other | Biological & Biomedical Sciences | Lab Report |