Gene Discovery for Complex Traits: Lessons from Africa (Case Study Sample)
This assignment is to read the article Gene Discovery for Complex Traits: Lessons from Africasource..
1 What is the citation for this article?
McClellan, J. M., Lehner, T., & King, M. C. (2017). Gene Discovery for Complex Traits: Lessons from Africa. Cell, 171(2), 261 264. ___________________________________________________________________________________________________________________________________________________________
* Jump straight to the introduction. When you're done reading the introduction, summarize the background in five sentences or less.
What contextual information do you need to understand the question asked? What work has been done before in this field to work toward answering the questions the authors are interested in? Why is the system the authors are using a good model to address these questions?
____ The genetics of African people are diverse and show complex traits when compared to non Africans. Research on genetics of schizophrenia among the Xhosa people of South Africa provides insights on the influence of gene-interaction environment. Beyond the study on the influence of genetics on schizophrenia, research on complex traits focusing on Africans yields various possibilities because of the contribution of African genes in genomic diversity. __________________________________________________________________________
b. What is the hypothesis?
Clearly articulate the hypothesis (even if the original authors neglected to do so in the paper). Why this hypothesis is relevant and interesting to the field of animal communication?
_____ In human genomic diversity, singling out genes associated with complex traits among African populations, will help identify
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