Literature Review Essay

Literature Review
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Article 1: Giannoni, M. F., Ciatti, R., Capaccia, L., Ruggiero, M., Dauri, M., & Mariani, P. P (2009). Total Knee Replacement: Prevention of Deep-Vein Thrombosis Using Pharmacological (Low-Molecular-Weight Heparin) and Mechanical (Intermittent Foot Sole Pump System) Combined Prophylaxis. Preliminary Results.
Summary of article: Giannoni et al. (2009) delved to establish the role of combined pharmacological and mechanical prophylaxis in preventing deep venous thrombosis following total knee replacement. Research elements: the researchers applied prospective case series study, and a total of 38 total knee replacement procedures were carried out on 34 patients, and four patients had bilateral TKR. The researchers gave patients injections of nadroparin calcium and these patients were then observed for 15 days. Outcomes/research results: the results obtained by Giannoni et al (2009) showed that nadroparin calcium reduced the incidence of DVT substantially. Significance to nursing and patient care: the findings of the study implied that nadroparin is effective in preventing DVT after TKR. As such, nadroparin should be the drug of choice by nurses in the prevention of DVT infections following TKR.
Article 2: Blanchard, Y., Meuwly, P., Leyvraz, M., Miron., Bounameaux, H., Hoffmeyer, P., Didier, D., & Schneider, P. (2010). Prevention of Deep-Vein Thrombosis after Total Knee Replacement. The Journal of Bone and Joint Surgery.
Summary of article: the best possible regime of antithrombotic prophylaxis for patients going through TKA is yet to be determined. Some surgeons employ LMWH which were chiefly developed for total hip arthroplasty, whilst other surgeons use intermittent pneumatic compression (Blanchard et al., 2010). The authors compared the safety as well as effectiveness of these 2 methods. Research elements: the researchers carried out a randomized study to compare these 2 techniques with blinded assessment of the endpoint by phlebography. A total of 130 patients were randomized who had been scheduled for elective total knee arthroplasty. A total of 108 patients consisting of 48 in the mechanical prophylaxis group and 60 in the LMWH group had phlebography 8 of twelve days following surgery. Out of the 47 patients who had DVT, 16 of them had LMWH and 31 of them had mechanical prophylaxis. Outcomes/research results: the dissimilarity between the 2 groups was very substantial. Significance to nursing and patient care: One every day subcutaneous injection of LMWH also known as calcium nadroparin in a weight-adjusted, fixed dose scheme is superior and safer relative to intermittent pneumatic compression of the foot for thromboprophylaxis following total knee arthroplasty (Blanchard et al., 2010).
Article 3: Warwick, D. (2012). Prevention of Venous Thromboembolism in Total Knee and Hip Replacement. Circulation.
Summary of article: there are a number of opti...